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RCSI21021 Biomedical Laboratory Sciences

Module Rationale

This module provides foundational knowledge in cellular biology and molecular genetics essential for medical students to understand human disease mechanisms.

Module Aims

To introduce key principles of cellular structure, genetic inheritance, transcription, and translation within a clinical context.

Year Lead

John McClane

Module Lead

Beth Middler

Credits

5
  1. Describe the ultrastructure and functions of primary cellular organelles.
  2. Explain the mechanisms of DNA replication, transcription, and translation in prokaryotes and eukaryotes.
  3. Analyze Mendelian inheritance patterns and calculate genetic probabilities in population genetics.
  4. Apply basic histological concepts to differentiate between major human tissue types.

Recommended Book Resources

  • Eldra Solomon, Charles Martin, Diana Martin, Linda Berg (2014), Biology, Cengage Learning, p. 1440, [ISBN: 9781285423586].
  • Daniel D. Chiras (2013), Human Biology, Jones & Bartlett Publishers, p. 593, [ISBN: 978-1284031812].
  • Bruce Alberts, Dennis Bray, Karen Hopkin (2014), Essential Cell Biology, Garland Pub, p. 865, [ISBN: 9780815345251].
  • Robert L. Nussbaum, Roderick R. McInnes (2016), Thompson & Thompson Genetics in Medicine, Elsevier Health Sciences, p. 546, [ISBN: 9781437706963].
  • Week 1: Biological molecules: Carbohydrates, Proteins, and Lipids
  • Week 2: Cell Ultrastructure: Cell Wall, Plasma Membranes, and Nucleus
  • Week 3: Cell Ultrastructure: Mitochondria, Endoplasmic Reticulum, and Ribosomes
  • Week 4: Cell Function: Membrane transport, Cell division, and the Cell cycle
  • Week 5: Basic histology: Cells, Tissues, Organs, and Organ Systems
  • Week 6: Genetics: DNA structure, replication, and basic flow of information
  • Week 7: Gene expression: Transcription and translation mechanisms
  • Week 8: Transmission genetics: Chromosomes, Meiosis, and Mendelian inheritance

  • M.C.Q.

    No. of questions = 40
    Pass Marks:
    50
    Worth: 40% of total

  • Short Notes Paper

    No. of questions = 5
    Pass Marks:
    50
    Worth: 50% of total

  • Continuous Assessment MCQ

    No. of questions = 15
    Pass Marks:
    50
    Worth: 10% of total
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